Cobo Center provides visitors with ADA accessibility. Parking spaces for the disabled using both regular vehicles and vans are available in all Cobo Center parking lots. Wheelchairs may be requested at the concourse Information Desk (upon availability.)

The north side of Cobo Center is accessible from the street with elevator access off of Congress Street near the parking garage. The south side of the venue can be accessed from the street level entrance near the Washington Boulevard turnabout.